Our Services: Precision Carbohydrate & Nucleoside Chemistry

At HKR Biotech Pvt. Ltd, we combine deep synthetic expertise with state-of-the-art analytical characterization. We support global research institutions, academia, and pharmaceutical companies with scalable, high-purity chemical solutions.

1

Custom Glycan Synthesis

We tackle the most challenging branched and linear carbohydrate structures. Our team provides:

  • Oligosaccharide Synthesis

    Milligram to gram scale synthesis of complex oligosaccharides related to tumor-associated carbohydrate antigens (TACAS), carbohydrate-based antigens for vaccine development, antigens needed in immunology, glycolipids, and Human milk oligosaccharides (HMOs).

  • Carbohydrate-based Impurities and Reference Standards

    In-stock impurities and custom synthesis of carbohydrate-based impurities.

  • Protected Sugar Building Blocks

    In-stock protected sugar building blocks and custom synthesis of protected sugars, monosaccharides, and disaccharides as per customer need.

2

Specialized Sugars for DNA & RNA Synthesis

We provide the foundational building blocks for next-generation oligonucleotide therapeutics.

  • Phosphoramidites & Nucleosides

    Custom synthesis of modified ribose and deoxyribose units.

  • Protected Building Blocks

    High-purity intermediates for solid-phase synthesis, including LNA, BNA, and 2'-modified derivatives.

  • Scale-up Production

    Seamless transition from R&D batches to pilot-scale manufacturing.

3

Advanced Glycan Analysis (NMR Services)

We provide comprehensive structural characterization to guarantee the identity and purity of your compounds.

  • 1D NMR Analysis

    Standard 1H, 13C, and 19F NMR for routine purity and structural characterisation.

  • 2D NMR Structural Elucidation

    Detailed mapping of complex branched glycans using advanced NMR techniques like COSY, HSQC, HMBC, and NOESY/ROESY to determine:

    • Anomeric configurations (alpha vs. beta linkages).
    • Sequence and branching patterns.
  • Full Technical Reports

    Every analysis includes a detailed spectrum interpretation.

4

GLycoconjugatation Synthesis Services

Enhance your glycans with functional handles for biological tracking, bioorthogonal applications, synthetic conjugate vaccines and drug delivery. We use proven chemistries for glycocujugation and develop new chemistries.

  • Glycoconjugates

    Linking glycans to proteins, peptides, or lipids (Glycoproteins/Glycolipids).

  • Labeling

    Incorporation of fluorophores, biotin, or isotopic labels (Deuterium, 13C, 15N).

  • Click Chemistry

    Synthesis of azido and alkyne-functionalized sugars for rapid bioorthogonal assembly.

Our Service Commitment

Global Shipping

Express worldwide delivery with full customs documentation.

Quality Assured

Every product is shipped with a comprehensive CoA and NMR/MS data.

Confidentiality

We operate under strict NDA/CDA protocols to protect customer IP.

Partner With Us Today

Ready to start your project? Our technical team is available for consultations to discuss your specific synthetic routes or analytical needs.